Serious medical and psychological disease have been found with sleep deprivation. Sleep quality can be a tool for assessment of disease. Certain sleep disorders are common in many endocrine diseases. Excess growth hormone can cause sleep apnea, Excessive androgens can worsen OSA (Obstructive sleep apnoea), as can hypothyroidism. Similarly, thyroid disorders can contribute to debilitating insomnia(sleeplessness), with profound daytime fatigue. Disruptive sleep is now associated with increased risk for diabetes and obesity.